Berberine

About bulk Berberine

Berberine is supplied as a Berberis aristata root extract powder, standardized to a minimum of 5% berberine by HPLC. It is sold in bulk by the kilogram, with pound and gram conversions available for quoting, and every lot is batch-numbered. Buyers comparing bulk berberine offers are usually weighing three things: the berberine assay and the method behind it, the botanical source, and the particle size. We quote against the specification you send and supply the current lot's certificate of analysis with the quotation, so all three can be checked against real material before a purchase order is raised. If your specification calls for a different assay or botanical source, send it to us and we will source and quote against it.

Berberine specifications

Specifications are taken from our own shipping and quality records. Figures are confirmed against the batch certificate of analysis at the time of quotation.

Formulating with Berberine

The powder is used in capsules, tablets and dry powder blends. It is specified at 95% through 80 mesh and is normally taken in at the blending stage; if it has to sit inside an existing blend or a particular dosage form, send that form and your target inclusion level with the enquiry and we will check the current lot against it before quoting. Loss on drying and ash are each specified at 5.0% maximum and total heavy metals at 10 ppm maximum, with E. coli, Salmonella and Staphylococcus specified negative. Those figures, and the assay itself, are confirmed per lot on the certificate of analysis, so design against the lot you actually receive rather than a generic data sheet.

Sourcing and quality control

The material is held in U.S. stock and ships from our domestic warehouse network. It is packed 25 kg per paper drum with two inner plastic bags, and the stated shelf life is 36 months from the date of manufacture in a well-closed container, away from moisture, direct sunlight and heat. Each lot carries its own batch number, and we supply that lot's certificate of analysis with the shipment or on request, so the assay, particle size and microbiology results tie back to the material in front of you. On repeat business, the same batch numbering lets you set one delivery against the last and trace a finished-goods batch back to the berberine that went into it. We source through vetted, cGMP-compliant manufacturing partners.

Frequently asked questions

Further reading

• How to Read a Certificate of Analysis for Bulk Ingredients